null

SMILES: Fc1cccc(c1)-c1cc2n(C3CC3)c3s[nH]c(=O)c3c(=O)c2cc1F

InChI Key: InChIKey=RYGQUNHPYQJBTQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 4 subunit A (Staphylococcus aureus)	BDBM50178920 (9-cyclopropyl-6-fluoro-7-(3-fluorophenyl)isothiazo...) Show SMILES Fc1cccc(c1)-c1cc2n(C3CC3)c3s[nH]c(=O)c3c(=O)c2cc1F Show InChI InChI=1S/C19H12F2N2O2S/c20-10-3-1-2-9(6-10)12-8-15-13(7-14(12)21)17(24)16-18(25)22-26-19(16)23(15)11-4-5-11/h1-3,6-8,11H,4-5H2,(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Achillion Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4				Bioorg Med Chem Lett 16: 1272-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.065 BindingDB Entry DOI: 10.7270/Q22R3R76
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50178920 (9-cyclopropyl-6-fluoro-7-(3-fluorophenyl)isothiazo...) Show SMILES Fc1cccc(c1)-c1cc2n(C3CC3)c3s[nH]c(=O)c3c(=O)c2cc1F Show InChI InChI=1S/C19H12F2N2O2S/c20-10-3-1-2-9(6-10)12-8-15-13(7-14(12)21)17(24)16-18(25)22-26-19(16)23(15)11-4-5-11/h1-3,6-8,11H,4-5H2,(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Achillion Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against wild type Escherichia coli gyrase				Bioorg Med Chem Lett 16: 1272-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.065 BindingDB Entry DOI: 10.7270/Q22R3R76
					More data for this Ligand-Target Pair