BDBM50178935 CHEMBL383422::N1-(2-((dimethylamino)methyl)phenyl)-4-methylbenzene-1,2-diamine

SMILES: CN(C)Cc1ccccc1Nc1ccc(C)cc1N

InChI Key: InChIKey=HWLVSITUDAPLNE-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50178935 (CHEMBL383422 | N1-(2-((dimethylamino)methyl)phenyl...) Show SMILES CN(C)Cc1ccccc1Nc1ccc(C)cc1N Show InChI InChI=1S/C16H21N3/c1-12-8-9-16(14(17)10-12)18-15-7-5-4-6-13(15)11-19(2)3/h4-10,18H,11,17H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from SERT				Bioorg Med Chem Lett 16: 1297-300 (2006) Article DOI: 10.1016/j.bmcl.2005.11.066 BindingDB Entry DOI: 10.7270/Q2Z037R6
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50178935 (CHEMBL383422 | N1-(2-((dimethylamino)methyl)phenyl...) Show SMILES CN(C)Cc1ccccc1Nc1ccc(C)cc1N Show InChI InChI=1S/C16H21N3/c1-12-8-9-16(14(17)10-12)18-15-7-5-4-6-13(15)11-19(2)3/h4-10,18H,11,17H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory activity against NET				Bioorg Med Chem Lett 16: 1297-300 (2006) Article DOI: 10.1016/j.bmcl.2005.11.066 BindingDB Entry DOI: 10.7270/Q2Z037R6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50178935 (CHEMBL383422 | N1-(2-((dimethylamino)methyl)phenyl...) Show SMILES CN(C)Cc1ccccc1Nc1ccc(C)cc1N Show InChI InChI=1S/C16H21N3/c1-12-8-9-16(14(17)10-12)18-15-7-5-4-6-13(15)11-19(2)3/h4-10,18H,11,17H2,1-3H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory activity against DAT				Bioorg Med Chem Lett 16: 1297-300 (2006) Article DOI: 10.1016/j.bmcl.2005.11.066 BindingDB Entry DOI: 10.7270/Q2Z037R6
					More data for this Ligand-Target Pair