BDBM50178980 CHEMBL3813726
SMILES: COc1ccc(CCN(CCCc2ccccc2Br)CCc2ccc3OCOc3c2)cc1OC
InChI Key: InChIKey=BINQFCRFCWOLJS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50178980 (CHEMBL3813726) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method | Bioorg Med Chem Lett 26: 3216-3219 (2016) BindingDB Entry DOI: 10.7270/Q29S1SXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50178980 (CHEMBL3813726) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method | Bioorg Med Chem Lett 26: 3216-3219 (2016) BindingDB Entry DOI: 10.7270/Q29S1SXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50178980 (CHEMBL3813726) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method | Bioorg Med Chem Lett 26: 3216-3219 (2016) BindingDB Entry DOI: 10.7270/Q29S1SXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50178980 (CHEMBL3813726) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 326 | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York Curated by ChEMBL | Assay Description Antagonist activity at human 5-HT2B receptor by PDSP assay | Bioorg Med Chem Lett 26: 3216-3219 (2016) BindingDB Entry DOI: 10.7270/Q29S1SXB | |||||||||||
More data for this Ligand-Target Pair |