BDBM50178999 2-(4-(4,6-bis(3,4-difluorophenylamino)-1,3,5-triazin-2-yl)piperazin-1-yl)ethanol::CHEMBL205085

SMILES: OCCN1CCN(CC1)c1nc(Nc2ccc(F)c(F)c2)nc(Nc2ccc(F)c(F)c2)n1

InChI Key: InChIKey=ZYWXNFFXBKUSNU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50178999 (2-(4-(4,6-bis(3,4-difluorophenylamino)-1,3,5-triaz...) Show SMILES OCCN1CCN(CC1)c1nc(Nc2ccc(F)c(F)c2)nc(Nc2ccc(F)c(F)c2)n1 Show InChI InChI=1S/C21H21F4N7O/c22-15-3-1-13(11-17(15)24)26-19-28-20(27-14-2-4-16(23)18(25)12-14)30-21(29-19)32-7-5-31(6-8-32)9-10-33/h1-4,11-12,33H,5-10H2,(H2,26,27,28,29,30)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair