BindingDB PrimarySearch

BDBM50179011 CHEMBL380456::Moracin P

SMILES: CC1(C)Oc2cc3oc(cc3cc2CC1O)-c1cc(O)cc(O)c1

InChI Key: InChIKey=QFUCSEIKNTUPPA-UHFFFAOYSA-N

Data: 8 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50179011
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50179011 (CHEMBL380456 \| Moracin P) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of HIF-1alpha in human Hep3B cells assessed as decrease in VEGF level after 20 hrs by ELISA				Eur J Med Chem 90: 379-93 (2015) Article DOI: 10.1016/j.ejmech.2014.11.047 BindingDB Entry DOI: 10.7270/Q2GF0W5F
Dongguk University-Seoul Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1 alpha (Homo sapiens (Human))	BDBM50179011 (CHEMBL380456 \| Moracin P) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus FabI-mediated trans-2-octenoyl N-acetylcysteamine (t-o-NAC thioester) substrate reduction assessed as decrease in...				Eur J Med Chem 90: 379-93 (2015) Article DOI: 10.1016/j.ejmech.2014.11.047 BindingDB Entry DOI: 10.7270/Q2GF0W5F
Dongguk University-Seoul Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1 alpha (Homo sapiens (Human))	BDBM50179011 (CHEMBL380456 \| Moracin P) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				Eur J Med Chem 90: 379-93 (2015) Article DOI: 10.1016/j.ejmech.2014.11.047 BindingDB Entry DOI: 10.7270/Q2GF0W5F
Dongguk University-Seoul Curated by ChEMBL					More data for this Ligand-Target Pair
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Rattus norvegicus)	BDBM50179011 (CHEMBL380456 \| Moracin P) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
Centre of Experimental Medicine SAS Curated by ChEMBL					Assay Description Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay				ACS Med Chem Lett 11: 1006-1013 (2020)
Centre of Experimental Medicine SAS Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50179011 (CHEMBL380456 \| Moracin P) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Bioscience and Biotechnology (KRIBB) Curated by ChEMBL					Assay Description Inhibition of PTP1B				Bioorg Med Chem Lett 16: 1426-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.071 BindingDB Entry DOI: 10.7270/Q2JQ10KT
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50179011 (CHEMBL380456 \| Moracin P) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
Dongguk University-Seoul Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50179011 (CHEMBL380456 \| Moracin P) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
Dongguk University-Seoul Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM50179011 (CHEMBL380456 \| Moracin P) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Bioscience and Biotechnology (KRIBB) Curated by ChEMBL					Assay Description Inhibition of VHR DS-PTP				Bioorg Med Chem Lett 16: 1426-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.071 BindingDB Entry DOI: 10.7270/Q2JQ10KT
					More data for this Ligand-Target Pair