BDBM50179131 (2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino)-3-methylhexa-2,4-dienoic acid::CHEMBL427391

SMILES: CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C

InChI Key: InChIKey=PQUKTZDZZRYNRP-XYJQQDCNSA-N

Data: 3 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50179131   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50179131 ((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...) Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity to RXRalpha				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50179131 ((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...) Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity to RXRgamma				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50179131 ((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...) Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	152	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity to RXRbeta				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50179131 ((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...) Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	117	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Transactivation of RXRbeta in CV1 cells by cotransfection assay				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50179131 ((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...) Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Transactivation of RXRalpha in CV1 cells by cotransfection assay				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50179131 ((2E,4E)-6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tet...) Show SMILES CCN(C\C=C\C(\C)=C\C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H35NO2/c1-8-25(13-9-10-17(2)14-22(26)27)21-16-20-19(15-18(21)3)23(4,5)11-12-24(20,6)7/h9-10,14-16H,8,11-13H2,1-7H3,(H,26,27)/b10-9+,17-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	125	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Transactivation of RXRgamma in CV1 cells by cotransfection assay				Bioorg Med Chem Lett 16: 2352-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.003 BindingDB Entry DOI: 10.7270/Q2S75FW3
					More data for this Ligand-Target Pair