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SMILES: COc1cc2Cc3c(Nc4ccc(Cl)cc4Cl)[nH]nc3-c2cc1OC

InChI Key: InChIKey=OEYHUXZATDICNL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179218   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50179218
PNG
(2,4-dichloro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,...)
Show SMILES COc1cc2Cc3c(Nc4ccc(Cl)cc4Cl)[nH]nc3-c2cc1OC
Show InChI InChI=1S/C18H15Cl2N3O2/c1-24-15-6-9-5-12-17(11(9)8-16(15)25-2)22-23-18(12)21-14-4-3-10(19)7-13(14)20/h3-4,6-8H,5H2,1-2H3,(H2,21,22,23)
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Similars
Article
PubMed
n/an/a 5.42E+3n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against PDGFRbeta kinase

J Med Chem 48: 8163-73 (2005)


Article DOI: 10.1021/jm050680m
BindingDB Entry DOI: 10.7270/Q2W095HW
More data for this
Ligand-Target Pair