BDBM50179222 3,4-dichloro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine::CHEMBL119910

SMILES: COc1cc2Cc3c(Nc4ccc(Cl)c(Cl)c4)[nH]nc3-c2cc1OC

InChI Key: InChIKey=QPOUDHAKEFGBQQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179222 (3,4-dichloro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,...) Show SMILES COc1cc2Cc3c(Nc4ccc(Cl)c(Cl)c4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H15Cl2N3O2/c1-24-15-6-9-5-12-17(11(9)8-16(15)25-2)22-23-18(12)21-10-3-4-13(19)14(20)7-10/h3-4,6-8H,5H2,1-2H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair