BDBM50179260 1-(3-(6-methoxynaphthalen-1-yl)propyl)-3,3-dimethylpiperidine hydrochloride::3,3-dimethyl-1-[3-(6-methoxynaphthalen-1-yl)propyl]piperidine hydrochloride::CHEMBL178326::CHEMBL537177

SMILES: COc1ccc2c(CCCN3CCCC(C)(C)C3)cccc2c1

InChI Key: InChIKey=PIILAVXTKIZGHR-UHFFFAOYSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50179260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50179260 (1-(3-(6-methoxynaphthalen-1-yl)propyl)-3,3-dimethy...) Show SMILES COc1ccc2c(CCCN3CCCC(C)(C)C3)cccc2c1 Show InChI InChI=1S/C21H29NO/c1-21(2)12-6-14-22(16-21)13-5-9-17-7-4-8-18-15-19(23-3)10-11-20(17)18/h4,7-8,10-11,15H,5-6,9,12-14,16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes				J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50179260 (1-(3-(6-methoxynaphthalen-1-yl)propyl)-3,3-dimethy...) Show SMILES COc1ccc2c(CCCN3CCCC(C)(C)C3)cccc2c1 Show InChI InChI=1S/C21H29NO/c1-21(2)12-6-14-22(16-21)13-5-9-17-7-4-8-18-15-19(23-3)10-11-20(17)18/h4,7-8,10-11,15H,5-6,9,12-14,16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membrane				J Med Chem 50: 4648-55 (2007) Article DOI: 10.1021/jm070373b BindingDB Entry DOI: 10.7270/Q2SQ917Z
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-delta(8),delta(7)-isomerase (Cavia porcellus)	BDBM50179260 (1-(3-(6-methoxynaphthalen-1-yl)propyl)-3,3-dimethy...) Show SMILES COc1ccc2c(CCCN3CCCC(C)(C)C3)cccc2c1 Show InChI InChI=1S/C21H29NO/c1-21(2)12-6-14-22(16-21)13-5-9-17-7-4-8-18-15-19(23-3)10-11-20(17)18/h4,7-8,10-11,15H,5-6,9,12-14,16H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes				J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50179260 (1-(3-(6-methoxynaphthalen-1-yl)propyl)-3,3-dimethy...) Show SMILES COc1ccc2c(CCCN3CCCC(C)(C)C3)cccc2c1 Show InChI InChI=1S/C21H29NO/c1-21(2)12-6-14-22(16-21)13-5-9-17-7-4-8-18-15-19(23-3)10-11-20(17)18/h4,7-8,10-11,15H,5-6,9,12-14,16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.02E+4	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Antiproliferative activity mediated by sigma 1 receptor in rat C6 glioma cells by MTT assay				J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J
					More data for this Ligand-Target Pair