BDBM50179269 1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)butyl)-4-methylpiperidine hydrochloride::CHEMBL540573

SMILES: COc1ccc2C(CCCCN3CCC(C)CC3)CCCc2c1

InChI Key: InChIKey=SOIXVSZRQJTOLM-UHFFFAOYSA-N

Data: 3 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50179269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50179269 (1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1ccc2C(CCCCN3CCC(C)CC3)CCCc2c1 Show InChI InChI=1S/C21H33NO/c1-17-11-14-22(15-12-17)13-4-3-6-18-7-5-8-19-16-20(23-2)9-10-21(18)19/h9-10,16-18H,3-8,11-15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes				J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50179269 (1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1ccc2C(CCCCN3CCC(C)CC3)CCCc2c1 Show InChI InChI=1S/C21H33NO/c1-17-11-14-22(15-12-17)13-4-3-6-18-7-5-8-19-16-20(23-2)9-10-21(18)19/h9-10,16-18H,3-8,11-15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Degli Studi di Bari ALDO MORO Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 mins				Eur J Med Chem 108: 577-85 (2016) BindingDB Entry DOI: 10.7270/Q22Z17C3
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-delta(8),delta(7)-isomerase (Cavia porcellus)	BDBM50179269 (1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1ccc2C(CCCCN3CCC(C)CC3)CCCc2c1 Show InChI InChI=1S/C21H33NO/c1-17-11-14-22(15-12-17)13-4-3-6-18-7-5-8-19-16-20(23-2)9-10-21(18)19/h9-10,16-18H,3-8,11-15H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes				J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50179269 (1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1ccc2C(CCCCN3CCC(C)CC3)CCCc2c1 Show InChI InChI=1S/C21H33NO/c1-17-11-14-22(15-12-17)13-4-3-6-18-7-5-8-19-16-20(23-2)9-10-21(18)19/h9-10,16-18H,3-8,11-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Degli Studi di Bari ALDO MORO Curated by ChEMBL					Assay Description Displacement of 5-(Dimethylamino)-2-(6-((5-(4-(4-methylpiperidin-1-yl)butyl)-5,6,7,8-tetrahydronaphthalen-2-yl)oxy)hexyl)isoindoline-1,3-dione from s...				Eur J Med Chem 108: 577-85 (2016) BindingDB Entry DOI: 10.7270/Q22Z17C3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50179269 (1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1ccc2C(CCCCN3CCC(C)CC3)CCCc2c1 Show InChI InChI=1S/C21H33NO/c1-17-11-14-22(15-12-17)13-4-3-6-18-7-5-8-19-16-20(23-2)9-10-21(18)19/h9-10,16-18H,3-8,11-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Degli Studi di Bari ALDO MORO Curated by ChEMBL					Assay Description Displacement of 5-(Dimethylamino)-2-{6-[(5-(4-(4-methylpiperidin-1-yl)butyl)naphthalen-2-yl)oxy]hexyl}isoindole-1,3-dione from sigma 1 receptor (unkn...				Eur J Med Chem 108: 577-85 (2016) BindingDB Entry DOI: 10.7270/Q22Z17C3
					More data for this Ligand-Target Pair