BDBM50179336 (4-methylpiperazin-1-yl)(6H-thieno[2,3-b]pyrrol-5-yl)methanone::CHEMBL362495

SMILES: CN1CCN(CC1)C(=O)c1cc2ccsc2[nH]1

InChI Key: InChIKey=SGZDOXGNMZGJPZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50179336 ((4-methylpiperazin-1-yl)(6H-thieno[2,3-b]pyrrol-5-...) Show SMILES CN1CCN(CC1)C(=O)c1cc2ccsc2[nH]1 Show InChI InChI=1S/C12H15N3OS/c1-14-3-5-15(6-4-14)12(16)10-8-9-2-7-17-11(9)13-10/h2,7-8,13H,3-6H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from recombinant human histamine H4 receptor in SK-N-MC cells				J Med Chem 48: 8289-98 (2005) Article DOI: 10.1021/jm0502081 BindingDB Entry DOI: 10.7270/Q2C24W00
					More data for this Ligand-Target Pair