BDBM50179339 (4,6-dichloro-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone::CHEMBL120221

SMILES: CN1CCN(CC1)C(=O)c1nc2cc(Cl)cc(Cl)c2[nH]1

InChI Key: InChIKey=VJLNEEAKLMXGQX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50179339 ((4,6-dichloro-1H-benzoimidazol-2-yl)(4-methylpiper...) Show SMILES CN1CCN(CC1)C(=O)c1nc2cc(Cl)cc(Cl)c2[nH]1 Show InChI InChI=1S/C13H14Cl2N4O/c1-18-2-4-19(5-3-18)13(20)12-16-10-7-8(14)6-9(15)11(10)17-12/h6-7H,2-5H2,1H3,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from recombinant human histamine H4 receptor in SK-N-MC cells				J Med Chem 48: 8289-98 (2005) Article DOI: 10.1021/jm0502081 BindingDB Entry DOI: 10.7270/Q2C24W00
					More data for this Ligand-Target Pair