BDBM50179347 (5-trifluoromethyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone::CHEMBL197477

SMILES: CN1CCN(CC1)C(=O)c1cc2cc(ccc2[nH]1)C(F)(F)F

InChI Key: InChIKey=RJTNRVNBDUTWPV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50179347 ((5-trifluoromethyl-1H-indol-2-yl)-(4-methyl-pipera...) Show SMILES CN1CCN(CC1)C(=O)c1cc2cc(ccc2[nH]1)C(F)(F)F Show InChI InChI=1S/C15H16F3N3O/c1-20-4-6-21(7-5-20)14(22)13-9-10-8-11(15(16,17)18)2-3-12(10)19-13/h2-3,8-9,19H,4-7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	412	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from recombinant human histamine H4 receptor in SK-N-MC cells				J Med Chem 48: 8289-98 (2005) Article DOI: 10.1021/jm0502081 BindingDB Entry DOI: 10.7270/Q2C24W00
					More data for this Ligand-Target Pair