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BDBM50179382 CHEMBL3814535

SMILES: CC(C)Cn1c(C)cc(NCc2ccc(cc2)C(F)(F)F)cc1=O

InChI Key: InChIKey=DQGLCUVKAXPIQI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179382   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-2A adrenergic receptor


(Homo sapiens (Human))		BDBM50179382
PNG
(CHEMBL3814535)
Show SMILES CC(C)Cn1c(C)cc(NCc2ccc(cc2)C(F)(F)F)cc1=O
Show InChI InChI=1S/C18H21F3N2O/c1-12(2)11-23-13(3)8-16(9-17(23)24)22-10-14-4-6-15(7-5-14)18(19,20)21/h4-9,12,22H,10-11H2,1-3H3
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PubMed
 5.80E+4n/an/an/an/an/an/an/an/a



University of Belgrade

Curated by ChEMBL


Assay Description
Displacement of [3H]RS-79948-197 from recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane by scintillation counting method

Bioorg Med Chem 24: 3174-83 (2016)


BindingDB Entry DOI: 10.7270/Q2NZ89J3
More data for this
Ligand-Target Pair