BDBM50179581 (+)-2-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-oxo-dodecahydronaphtho[2,3-c]furan-4-yl)vinyl)quinolin-6-yloxy)-N-phenylacetamide::CHEMBL382830

SMILES: C[C@H]1OC(=O)[C@@H]2C[C@@H]3CCCC[C@H]3[C@H](\C=C\c3ccc4cc(OCC(=O)Nc5ccccc5)ccc4n3)[C@H]12

InChI Key: InChIKey=BDBPAVHTWMVWHN-SORLVKKQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50179581 ((+)-2-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-ox...) Show SMILES C[C@H]1OC(=O)[C@@H]2C[C@@H]3CCCC[C@H]3[C@H](\C=C\c3ccc4cc(OCC(=O)Nc5ccccc5)ccc4n3)[C@H]12 Show InChI InChI=1S/C32H34N2O4/c1-20-31-27(26-10-6-5-7-21(26)18-28(31)32(36)38-20)15-13-24-12-11-22-17-25(14-16-29(22)33-24)37-19-30(35)34-23-8-3-2-4-9-23/h2-4,8-9,11-17,20-21,26-28,31H,5-7,10,18-19H2,1H3,(H,34,35)/b15-13+/t20-,21+,26-,27+,28-,31+/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]haTRAP from PAR1 in human platelet membrane				Bioorg Med Chem Lett 16: 1544-8 (2006) Article DOI: 10.1016/j.bmcl.2005.12.042 BindingDB Entry DOI: 10.7270/Q2KH0MXM
					More data for this Ligand-Target Pair