BDBM50179609 1-(5-(methylsulfonyl)pyridin-2-yl)-5-(phenylthio)-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile::CHEMBL381158

SMILES: CS(=O)(=O)c1ccc(nc1)-n1nc(c(C#N)c1Sc1ccccc1)C(F)(F)F

InChI Key: InChIKey=MZLHYYGDJPGEOW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50179609 (1-(5-(methylsulfonyl)pyridin-2-yl)-5-(phenylthio)-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(c(C#N)c1Sc1ccccc1)C(F)(F)F Show InChI InChI=1S/C17H11F3N4O2S2/c1-28(25,26)12-7-8-14(22-10-12)24-16(27-11-5-3-2-4-6-11)13(9-21)15(23-24)17(18,19)20/h2-8,10H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX1 by canine whole blood assay				Bioorg Med Chem Lett 16: 1202-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.110 BindingDB Entry DOI: 10.7270/Q2FT8KKM
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50179609 (1-(5-(methylsulfonyl)pyridin-2-yl)-5-(phenylthio)-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(c(C#N)c1Sc1ccccc1)C(F)(F)F Show InChI InChI=1S/C17H11F3N4O2S2/c1-28(25,26)12-7-8-14(22-10-12)24-16(27-11-5-3-2-4-6-11)13(9-21)15(23-24)17(18,19)20/h2-8,10H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX2 by canine whole blood assay				Bioorg Med Chem Lett 16: 1202-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.110 BindingDB Entry DOI: 10.7270/Q2FT8KKM
					More data for this Ligand-Target Pair