BDBM50179888 (3,4-Dichloro-phenyl)-(4-isoquinolin-5-yl-phthalazin-1-yl)-amine::CHEMBL205823::N-(3,4-dichlorophenyl)-4-(isoquinolin-5-yl)phthalazin-1-amine

SMILES: Clc1ccc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)cc1Cl

InChI Key: InChIKey=HQBJZNMKRRABTK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50179888 ((3,4-Dichloro-phenyl)-(4-isoquinolin-5-yl-phthalaz...) Show SMILES Clc1ccc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)cc1Cl Show InChI InChI=1S/C23H14Cl2N4/c24-20-9-8-15(12-21(20)25)27-23-19-6-2-1-5-18(19)22(28-29-23)17-7-3-4-14-13-26-11-10-16(14)17/h1-13H,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF method				Bioorg Med Chem 17: 731-40 (2009) Article DOI: 10.1016/j.bmc.2008.11.049 BindingDB Entry DOI: 10.7270/Q2W95929
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50179888 ((3,4-Dichloro-phenyl)-(4-isoquinolin-5-yl-phthalaz...) Show SMILES Clc1ccc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)cc1Cl Show InChI InChI=1S/C23H14Cl2N4/c24-20-9-8-15(12-21(20)25)27-23-19-6-2-1-5-18(19)22(28-29-23)17-7-3-4-14-13-26-11-10-16(14)17/h1-13H,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by HTRF assay				Bioorg Med Chem Lett 16: 1579-81 (2006) Article DOI: 10.1016/j.bmcl.2005.12.045 BindingDB Entry DOI: 10.7270/Q2WS8SVC
					More data for this Ligand-Target Pair