BDBM50180150 1-hydroxy-2-(4-phenylimidazol-1-yl)ethylidene-1,1-biphosphonic acid::CHEMBL438976

SMILES: OC(Cn1cnc(c1)-c1ccccc1)(P(O)(O)=O)P(O)(O)=O

InChI Key: InChIKey=SEXVQVXXIIQXET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hexokinase (Trypanosoma cruzi)	BDBM50180150 (1-hydroxy-2-(4-phenylimidazol-1-yl)ethylidene-1,1-...) Show SMILES OC(Cn1cnc(c1)-c1ccccc1)(P(O)(O)=O)P(O)(O)=O Show InChI InChI=1S/C11H14N2O7P2/c14-11(21(15,16)17,22(18,19)20)7-13-6-10(12-8-13)9-4-2-1-3-5-9/h1-6,8,14H,7H2,(H2,15,16,17)(H2,18,19,20)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Inhibitory activity against Trypanosoma cruzi hexokinase				J Med Chem 49: 215-23 (2006) Article DOI: 10.1021/jm0582625 BindingDB Entry DOI: 10.7270/Q2BV7G6G
					More data for this Ligand-Target Pair