BDBM50180251 1-((S)-2-aminopropyl)-1H-indazol-6-ol::CHEMBL371300

SMILES: C[C@H](N)Cn1ncc2ccc(O)cc12

InChI Key: InChIKey=WBYHTZYHAFNBKW-ZETCQYMHSA-N

Data: 15 KI  1 IC50  9 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50180251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]DOI from cloned human 5HT2C receptor expressed in CHO cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]DOI from cloned human 5HT2A receptor expressed in CHO cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in CHO cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	515	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against 5HT4 receptor				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from cloned human adrenergic alpha2A receptor expressed in Sf9 cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from cloned human adrenergic Alpha-2C receptor expressed in Sf9 cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against 5HT1D receptor				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against 5HT5A receptor				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against SERT				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against 5HT1B receptor				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against NET				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against 5HT6 receptor				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against adrenergic alpha-1B receptor				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against adrenergic alpha-1A receptor				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity at 5HT7 receptor expressed in human corneal epithelial CEPI-17-CL4 cells by adenylyl cyclase assay				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2b (5HT2A and 5HT2B) (RAT)	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2B receptor in longitudinal stomach fundus strips in wistar rats				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.70	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortex				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Agonistic activity at cloned human 5HT1A receptor expressed in CHO cells by inhibition of forskolin-induced cAMP production				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity at adrenergic alpha2A receptor expressed in human clonic adenocarcinoma HT29 cell by tissue contraction assay				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.05E+3	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity at adrenergic alpha-2B receptor expressed in opposum kidney OK cell by adenylyl cyclase assay				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity at adrenergic alpha2C receptor expressed in rat-mouse hybrid NH108-15 cell by adenylyl cyclase assay				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50180251 (1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...) Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12 Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity at adrenergic alpha-2A receptor expressed in human clonic adenocarcinoma HT29 cell by adenylyl cyclase assay				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair