BDBM50180276 CHEMBL3814939

SMILES: COc1cn(nc(-c2ccnn2-c2ccccc2)c1=O)C1CC1

InChI Key: InChIKey=YSLYWQSAFZJUQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50180276 (CHEMBL3814939) Show SMILES COc1cn(nc(-c2ccnn2-c2ccccc2)c1=O)C1CC1 Show InChI InChI=1S/C17H16N4O2/c1-23-15-11-20(12-7-8-12)19-16(17(15)22)14-9-10-18-21(14)13-5-3-2-4-6-13/h2-6,9-12H,7-8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human full length PDE10A2 expressed in African green monkey COS7 cells using [3H]cGMP as substrate preincubated for 30 mins followed by...				Bioorg Med Chem 24: 3447-55 (2016) BindingDB Entry DOI: 10.7270/Q2H9974G
					More data for this Ligand-Target Pair