BDBM50180386 3-(2-chloropyrimidin-4-yl)-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine::CHEMBL204390

SMILES: FC(F)(F)c1ccn2c(cnc2n1)-c1ccnc(Cl)n1

InChI Key: InChIKey=KVTRKSLNWMZSSN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50180386 (3-(2-chloropyrimidin-4-yl)-7-(trifluoromethyl)imid...) Show SMILES FC(F)(F)c1ccn2c(cnc2n1)-c1ccnc(Cl)n1 Show InChI InChI=1S/C11H5ClF3N5/c12-9-16-3-1-6(18-9)7-5-17-10-19-8(11(13,14)15)2-4-20(7)10/h1-5H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1175-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.112 BindingDB Entry DOI: 10.7270/Q2FN15SZ
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50180386 (3-(2-chloropyrimidin-4-yl)-7-(trifluoromethyl)imid...) Show SMILES FC(F)(F)c1ccn2c(cnc2n1)-c1ccnc(Cl)n1 Show InChI InChI=1S/C11H5ClF3N5/c12-9-16-3-1-6(18-9)7-5-17-10-19-8(11(13,14)15)2-4-20(7)10/h1-5H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1175-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.112 BindingDB Entry DOI: 10.7270/Q2FN15SZ
					More data for this Ligand-Target Pair