BDBM50180657 CHEMBL3819108

SMILES: Clc1ccc2n(CCc3nnn[nH]3)c3ccc(Cl)cc3c2c1

InChI Key: InChIKey=RSZNMJQGAJYWKW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Twik-RElated Potassium (K+) channel 1 (TREK1) (Homo sapiens (Human))	BDBM50180657 (CHEMBL3819108) Show SMILES Clc1ccc2n(CCc3nnn[nH]3)c3ccc(Cl)cc3c2c1 Show InChI InChI=1S/C15H11Cl2N5/c16-9-1-3-13-11(7-9)12-8-10(17)2-4-14(12)22(13)6-5-15-18-20-21-19-15/h1-4,7-8H,5-6H2,(H,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a
Universit£ Clermont Auvergne Curated by ChEMBL					Assay Description Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currents				J Med Chem 59: 5149-57 (2016) BindingDB Entry DOI: 10.7270/Q2319XSS
					More data for this Ligand-Target Pair