BDBM50180659 CHEMBL3818672
SMILES: CCCCCc1ccc(\C=C\C(=O)Nc2cc(Cl)ccc2C(O)=O)cc1
InChI Key: InChIKey=MDVFITMPFHDRBZ-JLHYYAGUSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Twik-RElated Potassium (K+) channel 1 (TREK1) (Homo sapiens (Human)) | BDBM50180659 (CHEMBL3818672) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
Universit£ Clermont Auvergne Curated by ChEMBL | Assay Description Activation of human TREK1 expressed in CHO cells assessed as increase in channel currents at +50 mV relative to control | J Med Chem 59: 5149-57 (2016) BindingDB Entry DOI: 10.7270/Q2319XSS | |||||||||||
More data for this Ligand-Target Pair |