BDBM50180697 6-[4-chloro-3-(2-hydroxy-ethoxy)-phenyl]-7-isopropyl-2-methyl-3H-quinazolin-4-one::CHEMBL380480

SMILES: CC(C)c1cc2nc(C)[nH]c(=O)c2cc1-c1ccc(Cl)c(OCCO)c1

InChI Key: InChIKey=SFLUCHRLEIGXBQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50180697 (6-[4-chloro-3-(2-hydroxy-ethoxy)-phenyl]-7-isoprop...) Show SMILES CC(C)c1cc2nc(C)[nH]c(=O)c2cc1-c1ccc(Cl)c(OCCO)c1 Show InChI InChI=1S/C20H21ClN2O3/c1-11(2)14-10-18-16(20(25)23-12(3)22-18)9-15(14)13-4-5-17(21)19(8-13)26-7-6-24/h4-5,8-11,24H,6-7H2,1-3H3,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	557	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assay				J Med Chem 49: 471-4 (2006) Article DOI: 10.1021/jm051058x BindingDB Entry DOI: 10.7270/Q2RX9BNT
					More data for this Ligand-Target Pair