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SMILES: Fc1ccc2nc([nH]c2c1)-c1ccccn1

InChI Key: InChIKey=AUSVDSQFCRIAEX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50180735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Core-binding factor subunit beta (Homo sapiens (Human))	BDBM50180735 (5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazole | 5...) Show SMILES Fc1ccc2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C12H8FN3/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,(H,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Patent Foundation US Patent					Assay Description We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...				US Patent US8748618 (2014) BindingDB Entry DOI: 10.7270/Q25M64C7
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50180735 (5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazole | 5...) Show SMILES Fc1ccc2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C12H8FN3/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Heidelberg Curated by ChEMBL					Assay Description Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 20: 4038-44 (2010) Article DOI: 10.1016/j.bmcl.2010.05.093 BindingDB Entry DOI: 10.7270/Q2RF5W0K
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50180735 (5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazole | 5...) Show SMILES Fc1ccc2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C12H8FN3/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Heidelberg Curated by ChEMBL					Assay Description Inhibition of human MetAP1				Bioorg Med Chem Lett 20: 4038-44 (2010) Article DOI: 10.1016/j.bmcl.2010.05.093 BindingDB Entry DOI: 10.7270/Q2RF5W0K
					More data for this Ligand-Target Pair
Methionine aminopeptidase (Escherichia coli (strain K12))	BDBM50180735 (5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazole | 5...) Show SMILES Fc1ccc2nc([nH]c2c1)-c1ccccn1 Show InChI InChI=1S/C12H8FN3/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,(H,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of Co2+ loaded MetAP expressed in Escherichia coli				J Med Chem 49: 511-22 (2006) Article DOI: 10.1021/jm050476z BindingDB Entry DOI: 10.7270/Q2N58KXD
					More data for this Ligand-Target Pair