BDBM50180795 CHEMBL3818069

SMILES: Cc1c(Cl)c(ccc1C(O)(C#CC1CC1)C(F)(F)F)C#N

InChI Key: InChIKey=VFRWEOOQPWKLNB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50180795 (CHEMBL3818069) Show SMILES Cc1c(Cl)c(ccc1C(O)(C#CC1CC1)C(F)(F)F)C#N Show InChI InChI=1S/C15H11ClF3NO/c1-9-12(5-4-11(8-20)13(9)16)14(21,15(17,18)19)7-6-10-2-3-10/h4-5,10,21H,2-3H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Modulation of human androgen receptor expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay				ACS Med Chem Lett 7: 83-8 (2016) BindingDB Entry DOI: 10.7270/Q2K35WMN
					More data for this Ligand-Target Pair