BDBM50180797 CHEMBL3818688

SMILES: Cc1c(Cl)c(ccc1C(O)(CC(C)(C)C)C(F)(F)F)C#N

InChI Key: InChIKey=SXTWECOWSIZHQC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50180797 (CHEMBL3818688) Show SMILES Cc1c(Cl)c(ccc1C(O)(CC(C)(C)C)C(F)(F)F)C#N Show InChI InChI=1S/C15H17ClF3NO/c1-9-11(6-5-10(7-20)12(9)16)14(21,15(17,18)19)8-13(2,3)4/h5-6,21H,8H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Modulation of human androgen receptor expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay				ACS Med Chem Lett 7: 83-8 (2016) BindingDB Entry DOI: 10.7270/Q2K35WMN
					More data for this Ligand-Target Pair