new BindingDB logo
myBDB logout

BDBM50180806 CHEMBL3818619

SMILES: OC(C1CC1)(c1ccc(C#N)c(Cl)c1Cl)C(F)(F)F

InChI Key: InChIKey=KDDDXOAYMREKOB-UHFFFAOYNA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180806   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen Receptor


(Homo sapiens (Human))
BDBM50180806
PNG
(CHEMBL3818619)
Show SMILES OC(C1CC1)(c1ccc(C#N)c(Cl)c1Cl)C(F)(F)F
Show InChI InChI=1/C12H8Cl2F3NO/c13-9-6(5-18)1-4-8(10(9)14)11(19,7-2-3-7)12(15,16)17/h1,4,7,19H,2-3H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 0.200n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Modulation of human androgen receptor expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay


ACS Med Chem Lett 7: 83-8 (2016)


BindingDB Entry DOI: 10.7270/Q2K35WMN
More data for this
Ligand-Target Pair