BDBM50180815 CHEMBL3818757

SMILES: Cc1c(C)c(ccc1C#N)C(O)(CC(C)(C)C)C(F)(F)F

InChI Key: InChIKey=SNDXHQNQRJBXOB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50180815 (CHEMBL3818757) Show SMILES Cc1c(C)c(ccc1C#N)C(O)(CC(C)(C)C)C(F)(F)F Show InChI InChI=1S/C16H20F3NO/c1-10-11(2)13(7-6-12(10)8-20)15(21,16(17,18)19)9-14(3,4)5/h6-7,21H,9H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Modulation of human androgen receptor expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay				ACS Med Chem Lett 7: 83-8 (2016) BindingDB Entry DOI: 10.7270/Q2K35WMN
					More data for this Ligand-Target Pair