BDBM50180823 CHEMBL3819048

SMILES: OC(C1CC1)(c1ccc(C#N)c(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=PZDOVCCZORXBKZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50180823 (CHEMBL3819048) Show SMILES OC(C1CC1)(c1ccc(C#N)c(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C13H9F6NO/c14-12(15,16)10-5-9(2-1-7(10)6-20)11(21,8-3-4-8)13(17,18)19/h1-2,5,8,21H,3-4H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.158	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Modulation of human androgen receptor expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay				ACS Med Chem Lett 7: 83-8 (2016) BindingDB Entry DOI: 10.7270/Q2K35WMN
					More data for this Ligand-Target Pair