BDBM50181087 CHEMBL206427::N-(3-(3-chlorobenzyloxy)-5-methylphenyl)-2-(2,6-difluorophenyl)-N-methylacetamide

SMILES: CN(C(=O)Cc1c(F)cccc1F)c1cc(C)cc(OCc2cccc(Cl)c2)c1

InChI Key: InChIKey=RATYBSYTTXELSZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181087 (CHEMBL206427 | N-(3-(3-chlorobenzyloxy)-5-methylph...) Show SMILES CN(C(=O)Cc1c(F)cccc1F)c1cc(C)cc(OCc2cccc(Cl)c2)c1 Show InChI InChI=1S/C23H20ClF2NO2/c1-15-9-18(12-19(10-15)29-14-16-5-3-6-17(24)11-16)27(2)23(28)13-20-21(25)7-4-8-22(20)26/h3-12H,13-14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffman-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from recombinant human mGlu5 receptor				Bioorg Med Chem Lett 16: 1892-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.088 BindingDB Entry DOI: 10.7270/Q2ZG6RT8
					More data for this Ligand-Target Pair