BDBM50181088 6-(azepan-1-yl)-N4,2-dicyclopropylpyrimidine-4,5-diamine::CHEMBL205482

SMILES: Nc1c(NC2CC2)nc(nc1N1CCCCCC1)C1CC1

InChI Key: InChIKey=JKAXYRSCMQDECT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50181088 (6-(azepan-1-yl)-N4,2-dicyclopropylpyrimidine-4,5-d...) Show SMILES Nc1c(NC2CC2)nc(nc1N1CCCCCC1)C1CC1 Show InChI InChI=1S/C16H25N5/c17-13-15(18-12-7-8-12)19-14(11-5-6-11)20-16(13)21-9-3-1-2-4-10-21/h11-12H,1-10,17H2,(H,18,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cells				Bioorg Med Chem Lett 16: 1834-9 (2006) Article DOI: 10.1016/j.bmcl.2006.01.006 BindingDB Entry DOI: 10.7270/Q2TQ613B
					More data for this Ligand-Target Pair