BDBM50181098 CHEMBL381259::N4-benzyl-N6,2-dicyclopropyl-5-methylpyrimidine-4,6-diamine

SMILES: Cc1c(NCc2ccccc2)nc(nc1NC1CC1)C1CC1

InChI Key: InChIKey=ORVIZUQZIOQNAO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50181098 (CHEMBL381259 | N4-benzyl-N6,2-dicyclopropyl-5-meth...) Show SMILES Cc1c(NCc2ccccc2)nc(nc1NC1CC1)C1CC1 Show InChI InChI=1S/C18H22N4/c1-12-16(19-11-13-5-3-2-4-6-13)21-18(14-7-8-14)22-17(12)20-15-9-10-15/h2-6,14-15H,7-11H2,1H3,(H2,19,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cells				Bioorg Med Chem Lett 16: 1834-9 (2006) Article DOI: 10.1016/j.bmcl.2006.01.006 BindingDB Entry DOI: 10.7270/Q2TQ613B
					More data for this Ligand-Target Pair