BDBM50181249 5-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(naphthalen-1-yl)-2,4-dioxoimidazolidin-1-yl)methyl)-2-(methylthio)benzonitrile::CHEMBL379900

SMILES: CSc1ccc(CN2C(=O)N(CCCn3ccnc3)C(=O)C2(C)c2cccc3ccccc23)cc1C#N

InChI Key: InChIKey=OMQYMCBJBYJVGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181249   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) Chain B (Homo sapiens (Human))	BDBM50181249 (5-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...) Show SMILES CSc1ccc(CN2C(=O)N(CCCn3ccnc3)C(=O)C2(C)c2cccc3ccccc23)cc1C#N Show InChI InChI=1S/C29H27N5O2S/c1-29(25-10-5-8-22-7-3-4-9-24(22)25)27(35)33(15-6-14-32-16-13-31-20-32)28(36)34(29)19-21-11-12-26(37-2)23(17-21)18-30/h3-5,7-13,16-17,20H,6,14-15,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Keimyung University Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 16: 1954-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.074 BindingDB Entry DOI: 10.7270/Q2280754
					More data for this Ligand-Target Pair