null

SMILES: OC(CC[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O)Cc1cccc(F)c1

InChI Key: InChIKey=RMYHMNDSXOKJLR-ZENAZSQFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Rattus norvegicus)	BDBM50181289 (5-(3-((S)-2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-...) Show SMILES OC(CC[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O)Cc1cccc(F)c1 Show InChI InChI=1S/C22H26FNO4S/c23-16-4-1-3-15(13-16)14-18(25)8-6-17-7-11-21(26)24(17)12-2-5-19-9-10-20(29-19)22(27)28/h1,3-4,9-10,13,17-18,25H,2,5-8,11-12,14H2,(H,27,28)/t17-,18?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to rat EP4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Rattus norvegicus)	BDBM50181289 (5-(3-((S)-2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-...) Show SMILES OC(CC[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O)Cc1cccc(F)c1 Show InChI InChI=1S/C22H26FNO4S/c23-16-4-1-3-15(13-16)14-18(25)8-6-17-7-11-21(26)24(17)12-2-5-19-9-10-20(29-19)22(27)28/h1,3-4,9-10,13,17-18,25H,2,5-8,11-12,14H2,(H,27,28)/t17-,18?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to rat EP2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Rattus norvegicus)	BDBM50181289 (5-(3-((S)-2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-...) Show SMILES OC(CC[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O)Cc1cccc(F)c1 Show InChI InChI=1S/C22H26FNO4S/c23-16-4-1-3-15(13-16)14-18(25)8-6-17-7-11-21(26)24(17)12-2-5-19-9-10-20(29-19)22(27)28/h1,3-4,9-10,13,17-18,25H,2,5-8,11-12,14H2,(H,27,28)/t17-,18?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat EP4 transfected in HEK293 cells by cAMP accumulation				Bioorg Med Chem Lett 16: 1799-802 (2006) Article DOI: 10.1016/j.bmcl.2006.01.018 BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5
					More data for this Ligand-Target Pair