Found 4 hits for monomerid = 50181314 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50181314
(4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)quinolin-...)Show InChI InChI=1S/C15H11N5O/c16-12-8-4-1-2-5-9(8)19-15(21)11(12)14-18-10-6-3-7-17-13(10)20-14/h1-7H,(H3,16,19,21)(H,17,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description Inhibitory activity against VEGFR1 |
Bioorg Med Chem Lett 16: 2247-51 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Mus musculus (mouse)) | BDBM50181314
(4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)quinolin-...)Show InChI InChI=1S/C15H11N5O/c16-12-8-4-1-2-5-9(8)19-15(21)11(12)14-18-10-6-3-7-17-13(10)20-14/h1-7H,(H3,16,19,21)(H,17,18,20) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description Inhibitory activity against PDGFRbeta |
Bioorg Med Chem Lett 16: 2247-51 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777 |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50181314
(4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)quinolin-...)Show InChI InChI=1S/C15H11N5O/c16-12-8-4-1-2-5-9(8)19-15(21)11(12)14-18-10-6-3-7-17-13(10)20-14/h1-7H,(H3,16,19,21)(H,17,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description Inhibitory activity against FGFR1 |
Bioorg Med Chem Lett 16: 2247-51 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50181314
(4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)quinolin-...)Show InChI InChI=1S/C15H11N5O/c16-12-8-4-1-2-5-9(8)19-15(21)11(12)14-18-10-6-3-7-17-13(10)20-14/h1-7H,(H3,16,19,21)(H,17,18,20) | PDB MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description Inhibitory activity against VEGFR2 |
Bioorg Med Chem Lett 16: 2247-51 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777 |
More data for this Ligand-Target Pair | |