BDBM50181337 2,5-dichloro-N-(5-methoxy-7-(4-methoxypyridin-3-yl)benzo[d]oxazol-2-yl)benzenesulfonamide::CHEMBL381536

SMILES: COc1cc(-c2cnccc2OC)c2oc(NS(=O)(=O)c3cc(Cl)ccc3Cl)nc2c1

InChI Key: InChIKey=ZQBRCVAWKXASLB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50181337 (2,5-dichloro-N-(5-methoxy-7-(4-methoxypyridin-3-yl...) Show SMILES COc1cc(-c2cnccc2OC)c2oc(NS(=O)(=O)c3cc(Cl)ccc3Cl)nc2c1 Show InChI InChI=1S/C20H15Cl2N3O5S/c1-28-12-8-13(14-10-23-6-5-17(14)29-2)19-16(9-12)24-20(30-19)25-31(26,27)18-7-11(21)3-4-15(18)22/h3-10H,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human FBPase1				Bioorg Med Chem Lett 16: 1807-10 (2006) Article DOI: 10.1016/j.bmcl.2006.01.014 BindingDB Entry DOI: 10.7270/Q2J965ZK
					More data for this Ligand-Target Pair