BDBM50181345 CHEMBL382008::N-(7-(3-(aminomethyl)phenyl)-5-methoxybenzo[d]oxazol-2-yl)-2,5-dichlorobenzenesulfonamide

SMILES: COc1cc(-c2cccc(CN)c2)c2oc(NS(=O)(=O)c3cc(Cl)ccc3Cl)nc2c1

InChI Key: InChIKey=DGHVDGRVOVHJGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50181345 (CHEMBL382008 | N-(7-(3-(aminomethyl)phenyl)-5-meth...) Show SMILES COc1cc(-c2cccc(CN)c2)c2oc(NS(=O)(=O)c3cc(Cl)ccc3Cl)nc2c1 Show InChI InChI=1S/C21H17Cl2N3O4S/c1-29-15-9-16(13-4-2-3-12(7-13)11-24)20-18(10-15)25-21(30-20)26-31(27,28)19-8-14(22)5-6-17(19)23/h2-10H,11,24H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human FBPase1				Bioorg Med Chem Lett 16: 1807-10 (2006) Article DOI: 10.1016/j.bmcl.2006.01.014 BindingDB Entry DOI: 10.7270/Q2J965ZK
					More data for this Ligand-Target Pair