BDBM50181376 CHEMBL372774::N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-4-phenylbutanamide

SMILES: O[C@H](Cc1ccccc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1

InChI Key: InChIKey=UKYQQDBFPUUGLN-HSZRJFAPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181376 (CHEMBL372774 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O[C@H](Cc1ccccc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C25H32N2O2/c28-23(19-20-7-2-1-3-8-20)24(29)26-15-6-16-27-17-13-25(14-18-27)12-11-21-9-4-5-10-22(21)25/h1-5,7-10,23,28H,6,11-19H2,(H,26,29)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair