BDBM50181378 (4R)-3-benzyl-N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-2-oxo-1,3-oxazolidine-4-carboxamide::CHEMBL202492

SMILES: O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1COC(=O)N1Cc1ccccc1

InChI Key: InChIKey=PYJICGWLSSEOBM-XMMPIXPASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181378 ((4R)-3-benzyl-N-(3-{2,3-dihydrospiro[indene-1,4'-p...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1COC(=O)N1Cc1ccccc1 Show InChI InChI=1S/C27H33N3O3/c31-25(24-20-33-26(32)30(24)19-21-7-2-1-3-8-21)28-15-6-16-29-17-13-27(14-18-29)12-11-22-9-4-5-10-23(22)27/h1-5,7-10,24H,6,11-20H2,(H,28,31)/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair