BDBM50181383 CHEMBL202067::N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-2,3-diphenylpropanamide

SMILES: O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C(Cc1ccccc1)c1ccccc1

InChI Key: InChIKey=LOKISLAKLXIIOW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181383 (CHEMBL202067 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C(Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H36N2O/c34-30(28(26-12-5-2-6-13-26)24-25-10-3-1-4-11-25)32-20-9-21-33-22-18-31(19-23-33)17-16-27-14-7-8-15-29(27)31/h1-8,10-15,28H,9,16-24H2,(H,32,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair