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SMILES: COc1ccccc1\C=C/C(=O)NCCCN1CCC2(CCc3ccccc23)CC1

InChI Key: InChIKey=XWZAXTMSNMGCNP-QXMHVHEDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181385   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))		BDBM50181385
PNG
((2Z)-N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine...)
Show SMILES COc1ccccc1\C=C/C(=O)NCCCN1CCC2(CCc3ccccc23)CC1
Show InChI InChI=1S/C26H32N2O2/c1-30-24-10-5-3-8-22(24)11-12-25(29)27-17-6-18-28-19-15-26(16-20-28)14-13-21-7-2-4-9-23(21)26/h2-5,7-12H,6,13-20H2,1H3,(H,27,29)/b12-11-
PDB

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Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells

J Med Chem 49: 847-9 (2006)


Article DOI: 10.1021/jm0509851
BindingDB Entry DOI: 10.7270/Q2DJ5F78
More data for this
Ligand-Target Pair