BDBM50181388 CHEMBL201694::N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-3-phenoxybenzamide

SMILES: OC(c1ccccc1)c1ccccc1C(=O)NCCCN1CCC2(CCc3ccccc23)CC1

InChI Key: InChIKey=XBDKDYYBHLUNSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181388 (CHEMBL201694 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES OC(c1ccccc1)c1ccccc1C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C30H34N2O2/c33-28(24-10-2-1-3-11-24)25-12-5-6-13-26(25)29(34)31-19-8-20-32-21-17-30(18-22-32)16-15-23-9-4-7-14-27(23)30/h1-7,9-14,28,33H,8,15-22H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair