BDBM50181399 CHEMBL427376::N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-1-phenyl-2,3-dihydro-1H-indole-2-carboxamide

SMILES: O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1Cc2ccccc2N1c1ccccc1

InChI Key: InChIKey=PWRGGYSBTFYLQT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181399   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181399 (CHEMBL427376 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1Cc2ccccc2N1c1ccccc1 Show InChI InChI=1S/C31H35N3O/c35-30(29-23-25-10-5-7-14-28(25)34(29)26-11-2-1-3-12-26)32-19-8-20-33-21-17-31(18-22-33)16-15-24-9-4-6-13-27(24)31/h1-7,9-14,29H,8,15-23H2,(H,32,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair