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SMILES: O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1OC(=O)N[C@H]1Cc1ccccc1

InChI Key: InChIKey=XREPEKUUXHOJKM-ZEQRLZLVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181402   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))		BDBM50181402
PNG
((4S,5S)-4-benzyl-N-(3-{2,3-dihydrospiro[indene-1,4...)
Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1OC(=O)N[C@H]1Cc1ccccc1
Show InChI InChI=1S/C27H33N3O3/c31-25(24-23(29-26(32)33-24)19-20-7-2-1-3-8-20)28-15-6-16-30-17-13-27(14-18-30)12-11-21-9-4-5-10-22(21)27/h1-5,7-10,23-24H,6,11-19H2,(H,28,31)(H,29,32)/t23-,24-/m0/s1
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n/an/a 30n/an/an/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells

J Med Chem 49: 847-9 (2006)


Article DOI: 10.1021/jm0509851
BindingDB Entry DOI: 10.7270/Q2DJ5F78
More data for this
Ligand-Target Pair