BDBM50181407 CHEMBL203247::N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-1,2,3,4-tetrahydronaphthalene-2-carboxamide

SMILES: O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1CCc2ccccc2C1

InChI Key: InChIKey=FFVHKELADRCBJW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181407 (CHEMBL203247 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1CCc2ccccc2C1 Show InChI InChI=1S/C27H34N2O/c30-26(24-11-10-21-6-1-2-8-23(21)20-24)28-16-5-17-29-18-14-27(15-19-29)13-12-22-7-3-4-9-25(22)27/h1-4,6-9,24H,5,10-20H2,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair