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SMILES: O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@@H]1CCCC[C@@H]1NC(=O)c1ccccc1

InChI Key: InChIKey=UUJCILFUAUVCOT-VPUSJEBWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181408   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))		BDBM50181408
PNG
(CHEMBL202455 | N-[(1S,2R)-2-[(3-{2,3-dihydrospiro[...)
Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@@H]1CCCC[C@@H]1NC(=O)c1ccccc1
Show InChI InChI=1S/C30H39N3O2/c34-28(24-10-2-1-3-11-24)32-27-14-7-5-12-25(27)29(35)31-19-8-20-33-21-17-30(18-22-33)16-15-23-9-4-6-13-26(23)30/h1-4,6,9-11,13,25,27H,5,7-8,12,14-22H2,(H,31,35)(H,32,34)/t25-,27+/m1/s1
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Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells

J Med Chem 49: 847-9 (2006)


Article DOI: 10.1021/jm0509851
BindingDB Entry DOI: 10.7270/Q2DJ5F78
More data for this
Ligand-Target Pair