BDBM50181411 CHEMBL369962::N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)bicyclo[4.2.0]octa-1(6),2,4-triene-7-carboxamide

SMILES: O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1Cc2ccccc12

InChI Key: InChIKey=XWOWAOGKMPUIDL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181411 (CHEMBL369962 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1Cc2ccccc12 Show InChI InChI=1S/C25H30N2O/c28-24(22-18-20-7-1-3-8-21(20)22)26-14-5-15-27-16-12-25(13-17-27)11-10-19-6-2-4-9-23(19)25/h1-4,6-9,22H,5,10-18H2,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair