BDBM50181414 CHEMBL201103::N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-3-[hydroxy(phenyl)methyl]pyridine-2-carboxamide

SMILES: OC(c1ccccc1)c1cccnc1C(=O)NCCCN1CCC2(CCc3ccccc23)CC1

InChI Key: InChIKey=SBEZGUMRMQPPQV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181414 (CHEMBL201103 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES OC(c1ccccc1)c1cccnc1C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C29H33N3O2/c33-27(23-9-2-1-3-10-23)24-11-6-17-30-26(24)28(34)31-18-7-19-32-20-15-29(16-21-32)14-13-22-8-4-5-12-25(22)29/h1-6,8-12,17,27,33H,7,13-16,18-21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair