BDBM50181416 CHEMBL372726::N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)-2-(naphthalen-1-yl)acetamide

SMILES: O=C(Cc1cccc2ccccc12)NCCCN1CCC2(CCc3ccccc23)CC1

InChI Key: InChIKey=KCTKCFSYQPMZKE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181416 (CHEMBL372726 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(Cc1cccc2ccccc12)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C28H32N2O/c31-27(21-24-10-5-9-22-7-1-3-11-25(22)24)29-17-6-18-30-19-15-28(16-20-30)14-13-23-8-2-4-12-26(23)28/h1-5,7-12H,6,13-21H2,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair